Personalized CRISPR therapies could soon reach thousands — here’s how

Publication details

Published 2026
Blood, Brain, Eye, Genomics, Delivery
University of California, Berkeley - IGI
Fyodor D Urnov, Sadik H Kassim
10.1038/d41586-026-01243-y
Nature . 2026 Apr;652(8111):857-859. doi: 10.1038/d41586-026-01243-y

Summary

Authors: Fyodor D Urnov, Sadik H Kassim

This Nature article explains how personalised treatments, using the CRISPR tool, could help more people with rare genetic conditions. The authors suggest testing similar treatments together, instead of treating each one as a completely new medicine.

This could save time and money while protecting patients. The article also points to the wider changes needed such as better data sharing, medicine production and teamwork between regulators, hospitals and developers.

Keywords: personalised CRISPR, rare genetic conditions, gene changing, approval rules, treatment testing, patient-matched medicine, data sharing