Delivery systems for CRISPR genome editors

University of Oxford (Cehajic-Kapetanovic) | UC Berkeley IGI (Wilson)

2025-2027

This project is investigating alternatives to adeno-associated viral (AAV) vectors, to deliver payloads to the eye.

AAVs have limited cargo capacity, can have undesirable long-term expression of the editor, and can have inflammatory side-effects. We will work with our partners at UC Berkeley to develop alternative solutions to AAV-mediated delivery to retina.